METTL3-mediated m6A modification maintains proper cell lineage specification during skin epithelium morphogenesis by coupling transcription and translation of key regulatory pathways.

EphrinB2/EphB4-mediated regulation of cytoskeletal contractility is a key homeostatic mechanism of lymphatic endothelial cell-cell junction maintenance, and provides a potential target for therapeutic modulation of lymphatic vessel permeability and function.

The utility of an in vitro cell culture system for studies of molecular mechanisms underlying the initial induction and subsequent propagation of environmentally induced epimutations is demonstrated.

Single-cell RNA-sequencing analyses and functional studies define heterogeneity within the pancreatic ductal tree and unique properties of subpopulations of duct cells including an epithelial-mesenchymal transcriptomic axis and roles in chronic pancreatic inflammation.

Prokaryotes use polycistronic messages for coordinated translation, whereas eukaryotic cells may achieve tunable protein synthesis by packaging monocistronic mRNAs into functional multiplexes via co-transcriptional interallelic coupling and non-canonical histone-H4 functions.

Cells from vertebrate and invertebrate model systems can be reprogrammed into stem-like cells using mouse genes.

Telomere dysfunction in iPSC-derived type II alveolar epithelial cells causes senescence and gene expression changes including Wnt-related changes that GSK3 inhibition can rescue, providing insight into pulmonary fibrosis pathogenesis.

A brain-wide map of neural activation reveals how sexual experience becomes a pair bond in the monogamous prairie vole.

Comprehensive analysis of alternative splicing from human droplet-based scRNA-seq data identifies genes with regulated splicing conserved in mouse and mouse lemur.

The causal link between capillary amyloid‑β accumulation in the brain and cerebrovascular dysfunction, previously established in the Tg‑SwDI mouse model, is to be mitigated and remains to be fully uncovered.