1,681 results found
    1. Cell Biology

    Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division

    Kie Itoh et al.
    Genetic and cell biological analyses reveal a new role of Drp1 in postsynaptic endocytosis during brain development beyond mitochondrial division GTPase.
    1. Ecology
    2. Neuroscience

    Genetic variation in the social environment affects behavioral phenotypes of oxytocin receptor mutants in zebrafish

    Diogo Ribeiro et al.
    Individual social behavior results from the interaction between the individuals own oxytocin receptor genotype and the oxytocin receptor genotypes of other individuals present in its social environment.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart

    Amy Heidersbach et al.
    microRNA-1 plays an essential role in the development and functioning of the heart by ensuring that genes for striated, rather than smooth, muscle are expressed there.
    1. Developmental Biology

    A gonad-expressed opsin mediates light-induced spawning in the jellyfish Clytia

    Gonzalo Quiroga Artigas et al.
    Gamete release in the jellyfish Clytia is mediated by an opsin photopigment expressed in neurosecretory cells of the gonad ectoderm, which release an oocyte maturation hormone in response to light.
    1. Neuroscience

    Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity

    Matthias Schlichting et al.
    Network silencing experiments and cell-specific CRISPR/Cas9 knockouts suggest that network communication is necessary for generating robust rhythms within the clock neuron network.
    1. Developmental Biology

    The REST remodeling complex protects genomic integrity during embryonic neurogenesis

    Tamilla Nechiporuk et al.
    The untimely loss of the transcriptional repressor REST from dividing neural progenitors during embryogenesis leads to compromised genomic integrity.
    1. Microbiology and Infectious Disease

    CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production performance

    Kui Xu et al.
    The double-gene-knockout pig is a valuable model to help understand the mechanisms of CD163 and pAPN in the infection of multiple viruses and offers excellent breeding materials for disease-resistant pigs.
    1. Genetics and Genomics
    2. Neuroscience

    A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes

    François Kroll et al.
    Zebrafish knockouts can be generated in a few hours directly from wild-type eggs and are suitable for studying continuous traits, including behaviour.
    1. Neuroscience

    Neuropeptide B mediates female sexual receptivity in medaka fish, acting in a female-specific but reversible manner

    Towako Hiraki-Kajiyama et al.
    In the brain of medaka fish, neuropeptide B acts directly downstream of estrogen in a female-specific but reversible manner to mediate female receptivity to male courtship.
    1. Neuroscience

    A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity

    TD Barbara Nguyen-Vu et al.
    Learning capacity depends on a dynamic interplay between the brain’s ability to change the strength of its synapses and the history of activity at those synapses.

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