1,221 results found
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Dissection of zebrafish shha function using site-specific targeting with a Cre-dependent genetic switch

    Kotaro Sugimoto et al.
    A versatile invertible gene trap vector is generated and inserted into a defined genomic locus in zebrafish via homologous recombination, demonstrating an efficient genetic approach to performing conditional knockout analysis.
    1. Cell Biology
    2. Neuroscience

    Piezo1 links mechanical forces to red blood cell volume

    Stuart M Cahalan et al.
    In red blood cells, the Piezo1 protein is responsible for sensing mechanical forces and volume regulation.
    1. Developmental Biology

    The REST remodeling complex protects genomic integrity during embryonic neurogenesis

    Tamilla Nechiporuk et al.
    The untimely loss of the transcriptional repressor REST from dividing neural progenitors during embryogenesis leads to compromised genomic integrity.
    1. Developmental Biology

    Neurogenesis: Give it a REST!

    Steven M Pollard, Maria Angeles Marques-Torrejon
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    1. Neuroscience

    Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106

    Barbara Celona et al.
    Zfp106 functions as an RNA binding protein, binds directly to GGGGCC RNA repeats, is required in motor neurons to prevent ALS-like neurodegeneration in mice, and can suppress neurotoxicity in an established fly model of ALS.
    1. Neuroscience

    Thermotaxis: Some like it hot, but not too hot

    Chloe Greppi et al.
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    1. Ecology
    2. Evolutionary Biology

    Evolutionary Morphology: One size does not fit all

    Diethard Tautz
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  1. Living Science: Triaging Shakespeare

    Indira M Raman
    What if every creative endeavor had to go through Peer Review? Indira M Rama considers the possibility.

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