Transgenic mice with high levels of FGF21 live for longer than wild-type mice and do so without reducing food intake.

A pattern recognition receptor called toll-like receptor 13 detects pathogens in a manner that is different to that seen in other pathogen sensors.

A combination of cellular, biochemical, genetic and genomic techniques have revealed a new molecular player in the production of fat cells in mice, which could improve our understanding of obesity.

The HITS-CLIP sequencing method is used to demonstrate that cryptic exons can detect messenger RNA that contains nonsense mutations, and then cause this RNA to decay, which shows that these exons are involved in maintaining the electrical balance of neurons and, possibly, preventing epilepsy.

The nematode worm C. elegans consumes familiar bacterial species more rapidly than it does novel ones, and this preference for familiarity is mediated by a pair of serotonergic neurons.

A transmembrane protein uses distinct mechanisms to regulate the movement of specific toll-like receptors-key immune system components involved in detecting pathogens-to their final locations inside cells.

A cellular motor protein helps to ensure that microtubules are oriented correctly within neuronal dendrites

The Notch signaling pathway has a central role in the formation of the circuit that controls egg-laying in the nematode worm C. elegans.

Sugar levels in leaves act as a signal for plants to switch from their juvenile to their adult form by regulating the expression of two genes.