2,578 results found
    1. Neuroscience

    Acetic acid activates distinct taste pathways in Drosophila to elicit opposing, state-dependent feeding responses

    Anita V Devineni et al.
    A single taste input, acetic acid, elicits opposing behavioral outputs depending on a fly's hunger state.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence

    Pavan Vedula et al.
    CRISPR/Cas9 gene editing in mice reveals that diverse functions of actin isoforms are defined by their nucleotide, rather than their amino acid sequence, suggesting a novel mechanism of nucleotide-dependent protein regulation in eukaryotic genomes.
    1. Ecology

    Dynamic metabolic exchange governs a marine algal-bacterial interaction

    Einat Segev et al.
    Physical and chemical interactions with bacteria influence the life and death of Emiliania huxleyi, a bloom-forming micro-alga important in global biogeochemical cycles.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Isoforms: Fundamental differences

    Peter W Gunning, Edna C Hardeman
    The differences between β- and γ-actin are deeper than those between the amino acid sequences of these two proteins.
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    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A common bacterial metabolite elicits prion-based bypass of glucose repression

    David M Garcia et al.
    Activity-guided fractionation identifies the first bacterial metabolite that potently induces a prion in nature.
    1. Plant Biology

    Homeostasis of branched-chain amino acids is critical for the activity of TOR signaling in Arabidopsis

    Pengfei Cao et al.
    Despite BCAAs being de novo-synthesized in chloroplasts, TOR activation by BCAAs is conserved in plants and triggers a re-organization of actin and actin-associated endomembranes.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    A selectivity filter at the intracellular end of the acid-sensing ion channel pore

    Timothy Lynagh et al.
    Sodium selectivity of acid-sensing ion channels is mediated by negatively charged side chains and not by a size-exclusion mechanism.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Bacterial Proliferation: Off the wall

    Dennis Claessen, Gilles P van Wezel
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    1. Cell Biology
    2. Evolutionary Biology

    Vesicle Coat Proteins: Finding the missing link

    Thomas U Schwartz
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