4,153 results found
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A new protocol for single-cell RNA-seq reveals stochastic gene expression during lag phase in budding yeast

    Abbas Jariani et al.
    A new high-throughput method for single-cell RNA-seq in yeast cells shows how stochastic expression of glucose-repressed genes contributes to cell-to-cell differences during adaptation to an environmental change.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Attacks on genetic privacy via uploads to genealogical databases

    Michael D Edge, Graham Coop
    Direct-to-consumer genetic genealogy services that allow users to upload their own datasets are vulnerable to attacks on genetic privacy that exploit the structure of genetic variation.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Transition between fermentation and respiration determines history-dependent behavior in fluctuating carbon sources

    Bram Cerulus et al.
    Live-cell microscopy and genome-wide screens reveal how slow transitions in metabolism can underlie metabolic memory, providing a model for organisms demonstrating similar history-dependent behaviour and routes to improve industrial microbes.
    1. Neuroscience

    Push-pull competition between bottom-up and top-down auditory attention to natural soundscapes

    Nicholas Huang, Mounya Elhilali
    Everyday soundscapes dynamically engage attention towards target sounds or salient ambient events, with both attentional forms engaging the same fronto-parietal network but in a push-pull competition for limited neural resources.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    An advanced cell cycle tag toolbox reveals principles underlying temporal control of structure-selective nucleases

    Julia Bittmann et al.
    The development of an advanced cell cycle tag toolbox will enable a wide variety of cell cycle studies and shows post-replicative function of nucleases resolving replication/recombination structures.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A composition-dependent molecular clutch between T cell signaling condensates and actin

    Jonathon A Ditlev et al.
    Compositional changes alter actin binding by phase separated T cell signaling clusters, enabling cluster movement by distinct actin networks.
    1. Neuroscience

    Cerebellar patients have intact feedback control that can be leveraged to improve reaching

    Amanda M Zimmet et al.
    A control system model of cerebellar patients' movements provides insight into the cerebellum's role in reaching and informs a virtual reality intervention to improve patient reaches.
    1. Neuroscience

    mPFC spindle cycles organize sparse thalamic activation and recently active CA1 cells during non-REM sleep

    Carmen Varela, Matthew A Wilson
    Sleep spindles provide a temporal framework to organize the reactivation of behaviorally relevant CA1 cells and sparsely active cells in the limbic thalamus.
    1. Neuroscience
    2. Physics of Living Systems

    Tuning of feedforward control enables stable muscle force-length dynamics after loss of autogenic proprioceptive feedback

    Joanne C Gordon et al.
    Running guinea fowl maintain stable running after loss of the stretch reflex in a major ankle extensor muscle, by increasing feedforward muscle activation to maintain ankle stiffness and work output.
    1. Ecology
    2. Microbiology and Infectious Disease

    Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance

    Andrés Aranda-Díaz et al.
    Shifts in pH that result from metabolic interactions between members of the Drosophila gut microbiota were sufficient to modulate Lactobacillus plantarum tolerance to the antibiotics rifampin and erythromycin.

Refine your results by:

Type
Research categories