The first survey of the complete morphologies of nerve endings in the skin of mice has revealed enormous structural diversity.

The Notch signaling pathway has a central role in the formation of the circuit that controls egg-laying in the nematode worm C. elegans.

The ability of an enzyme called XPD helicase to unwind the double helix is influenced by the DNA sequence and the availability of energy.

The recycling of transmitter vesicles at synapses shows calcium-dependent regulation that depends on the phosphorylation status of an enzyme called dynamin.

High-resolution optical microscopy is used to reveal the organization of extracellular matrix proteins within the basement membrane of the blood filtration barrier in the kidney at the nanometer scale.

PTBP2 ensures that adult protein variants are expressed only in mature neurons through regulation of alternative splicing during early neuronal development.

Contrary to the common belief that cognitive event-related potentials are generated by local activity within the cerebral cortex, it is shown that some of these potentials are modulated by subcortical inputs.

A chemical method has been developed for studying single organ regeneration and fate specification of stem cells in an adult organism.

Flow cytometric isolation and fate mapping shows that neurosphere-initiating cells are highly mitotically active and persist only transiently in vivo, and are distinct from quiescent, long-lived neural stem cells.

The kinase GSK-3 regulates cortical neuronal migration and dendritic orientation by phosphorylating key cytoskeletal proteins.