Browse the search results

Page 2 of 158
    1. Neuroscience

    Timing of the reticular lamina and basilar membrane vibration in living gerbil cochleae

    Wenxuan He, David Kemp, Tianying Ren
    Heterodyne low-coherence interferometry demonstrates that the latency of the sound-induced reticular lamina vibration is significantly greater than that of the basilar membrane vibration in living gerbil cochleae.
    1. Cell Biology

    PLK-1 promotes the merger of the parental genome into a single nucleus by triggering lamina disassembly

    Griselda Velez-Aguilera, Sylvia Nkombo Nkoula ... Lionel Pintard
    The polo-like kinase (Plk1) phophorylates the C. elegans lamin LMN-1 to promote timely lamina disassembly, which is essential for the merging of the parental chromosomes at the beginning of life.
    1. Neuroscience

    Mechanical overstimulation causes acute injury and synapse loss followed by fast recovery in lateral-line neuromasts of larval zebrafish

    Melanie Holmgren, Michael E Ravicz ... Lavinia Sheets
    Mechanically induced injury of zebrafish lateral-line organs shares key features of damage observed in noise-exposed mammalian ears, such as inflammation and synapse loss, yet, unlike mammals, rapidly repairs following damage.
    1. Evolutionary Biology

    Geological and taphonomic context for the new hominin species Homo naledi from the Dinaledi Chamber, South Africa

    Paul HGM Dirks, Lee R Berger ... Steven Tucker
    A new hominin species found in a South African cave is part of one of the most unusual hominin fossil assemblages on record.
    1. Neuroscience

    A long non-coding RNA is required for targeting centromeric protein A to the human centromere

    Delphine Quénet, Yamini Dalal
    A non-coding RNA-based targeting mechanism could potentially epigenetically maintain specialized chromatin structures, such as the centromere, in vivo.
    1. Neuroscience

    Spike-phase coupling patterns reveal laminar identity in primate cortex

    Zachary W Davis, Nicholas M Dotson ... John H Reynolds
    By examining the relationship between spike timing and the phase of the LFP across cortical layers, researchers can use a stereotyped phase-coupling pattern as a diagnostic marker for electrode depth when other methods of electrode placement are ambiguous.
    1. Developmental Biology

    Notch signaling and Bsh homeodomain activity are integrated to diversify Drosophila lamina neuron types

    Chundi Xu, Tyler B Ramos ... Chris Q Doe
    Notch signaling specifies binary neuronal fates through its integration with primary homeodomain activity.
    1. Evolutionary Biology

    Structural color in Junonia butterflies evolves by tuning scale lamina thickness

    Rachel C Thayer, Frances I Allen, Nipam H Patel
    Artificial selection on wing color and CRISPR/Cas9 knockout of the optix gene both alter scale lamina thickness in Junonia coenia, which shifts structural color wavelength and mimics macroevolutionary butterfly diversity.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations

    Pei-Ling Tsai, Chenguang Zhao ... Christian Schlieker
    Lamin B receptor may provide a long-sought model system enabling unprecedented studies of protein quality control in the nuclear envelope of mammalian cells.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    OpenNucleome for high-resolution nuclear structural and dynamical modeling

    Zhuohan Lao, Kartik D Kamat ... Bin Zhang
    An open-source tool for computational simulations of the human genome has been introduced, enabling the characterization of complex nuclear environments and the interpretation of experimental observations.