207 results found
    1. Ecology

    A SLC4 family bicarbonate transporter is critical for intracellular pH regulation and biomineralization in sea urchin embryos

    Marian Y Hu, Jia-Jiun Yan ... Meike Stumpp
    Cellular carbon accumulation systems are a fundamental prerequisite for biomineralization to stabilize pH and to supply inorganic carbon for CaCO3 precipitation under changing environmental conditions.
    1. Developmental Biology
    2. Evolutionary Biology

    Single-cell RNA sequencing of the Strongylocentrotus purpuratus larva reveals the blueprint of major cell types and nervous system of a non-chordate deuterostome

    Periklis Paganos, Danila Voronov ... Maria Ina Arnone
    Reconstruction of cell-type families in the purple sea urchin larva reveals unprecedented transcriptional diversity, stunning neuronal complexity and a missing link to pancreas evolution, suggesting this approach can be also used to uncover hidden cell type homologies.
    1. Developmental Biology
    2. Evolutionary Biology

    Architecture and evolution of the cis-regulatory system of the echinoderm kirrelL gene

    Jian Ming Khor, Charles A Ettensohn
    The transcriptional control system of a sea urchin gene reveals the deep evolutionary conservation of a gene regulatory network underlying morphogenesis.
    1. Cell Biology
    2. Neuroscience

    Desmosomal connectomics of all somatic muscles in an annelid larva

    Sanja Jasek, Csaba Verasztó ... Gáspár Jékely
    Volume-EM reconstruction of a whole-body desmosomal connectome including all muscles and their desmosomal partners in a Platynereis larva provides a detailed view of the organisation of the entire locomotor system in an animal.
    1. Developmental Biology
    2. Evolutionary Biology

    ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis

    Eman Hijaze, Tsvia Gildor ... Smadar Ben-Tabou de-Leon
    ROCK and the actomyosin network are essential for multiple aspects of sea urchin skeletogenesis, suggesting an independent deployment of these factors in biomineralization across Eukaryotes.
    1. Cell Biology
    2. Neuroscience

    Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction

    Qi Wang, Tae Hee Han ... Mihaela Serpe
    Characterization of Tnc as a selective integrin ligand at the Drosophila NMJ allows for unprecedented insights into our understanding of extracellular matrix/integrin interactions at synaptic locations and reveals novel, distinct presynaptic and postsynaptic integrin functions.
    1. Genetics and Genomics

    Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility

    Sophie Debaenst, Tamara Jarayseh ... Andy Willaert
    Revised
    Reviewed Preprint v2
    Updated
    1. Cell Biology
    2. Developmental Biology

    Mechanical force regulates tendon extracellular matrix organization and tenocyte morphogenesis through TGFbeta signaling

    Arul Subramanian, Lauren Fallon Kanzaki ... Thomas Friedrich Schilling
    Perturbation of mechanical force at muscle attachments and its effects on tendon morphogenesis provides insights into the mechanisms underlying cellular responses to tensional force and resulting extracellular matrix production.
    1. Neuroscience

    The wiring diagram of a glomerular olfactory system

    Matthew E Berck, Avinash Khandelwal ... Albert Cardona
    The complete neural circuit map of a tractable olfactory system will support studies towards bridging the gap between circuits and behavior.
    1. Neuroscience

    Morphology and synapse topography optimize linear encoding of synapse numbers in Drosophila looming responsive descending neurons

    Anthony Moreno-Sanchez, Alexander N Vasserman ... Jessica Ausborn
    Not revised
    Reviewed Preprint v1

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