8,164 results found
    1. Neuroscience

    Cortical RORβ is required for layer 4 transcriptional identity and barrel integrity

    Erin A Clark et al.
    RORβ is a key layer 4 transcription factor orchestrating a critical juncture in barrel development where terminal differentiation and activity inputs are integrated to drive cellular organization in the cortex.
    1. Neuroscience

    A genuine layer 4 in motor cortex with prototypical synaptic circuit connectivity

    Naoki Yamawaki et al.
    New evidence challenges the long-held view that motor cortex lacks a fourth layer, and reveals that its circuitry resembles that of other cortical regions more than previously thought.
    1. Developmental Biology
    2. Neuroscience

    Identity of neocortical layer 4 neurons is specified through correct positioning into the cortex

    Koji Oishi et al.
    Layer 4 neuronal identity is specified by Protocadherin20 positioning the neurons into layer 4 so that they receive a positional cue from thalamocortical axons.
    1. Neuroscience

    Ultrastructural heterogeneity of layer 4 excitatory synaptic boutons in the adult human temporal lobe neocortex

    Rachida Yakoubi et al.
    Neocortical synapses in layer 4 of the human temporal lobe neocortex were quantitatively characterized, at the subcellular level, using high-end, high-resolution electron microscopy and 3D-volume reconstructions.
    1. Neuroscience

    Low-noise encoding of active touch by layer 4 in the somatosensory cortex

    Samuel Andrew Hires et al.
    Touch information is represented with minimal noise in the somatosensory cortex during tactile exploration.
    1. Neuroscience

    Thalamic input to auditory cortex is locally heterogeneous but globally tonotopic

    Sebastian A Vasquez-Lopez et al.
    Layers 1 and 3b/4 of auditory cortex receive surprisingly heterogeneous but tonotopically matching input from the thalamus.
    1. Neuroscience

    Binocular matching of thalamocortical and intracortical circuits in the mouse visual cortex

    Yu Gu, Jianhua Cang
    The binocular matching of thalamic inputs to layer 4 cortical neurons initiates before that of intracortical inputs.
    1. Neuroscience

    Three rules govern thalamocortical connectivity of fast-spike inhibitory interneurons in the visual cortex

    Yulia Bereshpolova et al.
    In the visual system, three rules guide the thalamocortical connectivity of cortical fast-spike interneurons and are key to understand the potent and broadly tuned feed-forward inhibition that they generate.
    1. Neuroscience

    Behavioral-state modulation of inhibition is context-dependent and cell type specific in mouse visual cortex

    Janelle MP Pakan et al.
    The three main types of inhibitory neurons in mouse primary visual cortex respond differently to locomotion in darkness and during visual stimulation, revealing context-dependent responses to changes in behavioral state.
    1. Neuroscience

    Circuit organization of the excitatory sensorimotor loop through hand/forelimb S1 and M1

    Naoki Yamawaki et al.
    Cell-type-specific circuit analysis reveals a highly polysynaptic pattern of excitatory feedforward connections along the somatosensory-to-motor loop, from cuneate via VPL thalamus to S1 and M1 cortex and corticospinal neurons.

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