4,905 results found
    1. Neuroscience

    The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

    Andrew Lutas et al.
    Basal ganglia output neurons use the NALCN leak channel to maintain their characteristic tonic firing, and this channel is important for the modulation of firing by metabolic or receptor-mediated signals.
    1. Neuroscience

    Ionic mechanisms underlying history-dependence of conduction delay in an unmyelinated axon

    Yang Zhang et al.
    Conduction velocity of action potentials in unmyelinated axons depends ultimately on the gating variables of the fast voltage-gated sodium current and can be predicted from the action potential peak and trough voltages.
  1. Point of view: Motivating participation in open science by examining researcher incentives

    Sarah E Ali-Khan et al.
    A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.
    1. Epidemiology and Global Health

    Malaria: Age, exposure and immunity

    Michael White, James Watson
    The acquisition of immunity to malaria by an individual depends on their age and the number of infectious mosquito bites they have received.
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    1. Neuroscience

    Neuromodulation: Transcranial electric stimulation seen from within the brain

    Angel V Peterchev
    Computer models can make transcranial electric stimulation a better tool for research and therapy.
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    1. Cell Biology
    2. Microbiology and Infectious Disease

    Point of View: Is cell size a spandrel?

    Ariel Amir
    Analysis of experiments on bacteria suggests that the dependence of cell size on growth rate is not an adaptation but a causal consequence of a regulatory mechanism that controls DNA replication.

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