183 results found
    1. Cell Biology
    2. Neuroscience

    Pharmacological brake-release of mRNA translation enhances cognitive memory

    Carmela Sidrauski, Diego Acosta-Alvear ... Peter Walter
    A compound that prevents stressors such as UV light and viral infection from downregulating protein synthesis inside cells improves memory performance in mice.
    1. Neuroscience

    Dismantling the Papez circuit for memory in rats

    Seralynne D Vann
    In contrast to current models, inputs from midbrain limbic structures, but not from the hippocampus, are necessary for mammillary body contributions to memory.
    1. Neuroscience

    Learning: Hippocampal neurons wait their turn

    Yuan Gao, Ian Davison
    Version of Record
    Insight
    1. Neuroscience

    CA1 cell activity sequences emerge after reorganization of network correlation structure during associative learning

    Mehrab N Modi, Ashesh K Dhawale, Upinder S Bhalla
    As mice learn to associate events separated in time, neurons within the CA1 region of the hippocampus progressively reorganize their firing patterns, leading to a relay of cellular activity that bridges the two events.
    1. Neuroscience

    The inhibitory microcircuit of the substantia nigra provides feedback gain control of the basal ganglia output

    Jennifer Brown, Wei-Xing Pan, Joshua Tate Dudman
    Negative feedback signals within the substantia nigra regulate the output of the basal ganglia, with implications for disorders such as Parkinson's disease.
    1. Neuroscience

    Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall

    Il Hwan Kim, Hong Wang ... Ryohei Yasuda
    Conditional knockout of the small GTPase Cdc42 in excitatory neurons of the mouse forebrain leads to impaired long-term synaptic plasticity and impaired retrieval of remote memory.
    1. Neuroscience

    Learning and Memory: Taking a new look at how flies learn

    Benjamin Kottler, Bruno van Swinderen
    Version of Record
    Insight

  8. Decoding behaviour: an interview with Fanny Cazettes

    Fanny Cazettes grew up in the south of France and majored in biomedical engineering at the Institut Superieur des BioSciences (ISBS) in Paris. She is currently a PhD student at the Albert Einstein College of Medicine in New York, where she investigates neural activity in owls using physiological, behavioural and computational modelling techniques. She will be applying for a postdoctoral position within the next few months.
    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: New opportunities at the wild frontier

    Jane Alfred, Ian T Baldwin
    A better understanding of the natural history of model organisms will increase their value as model systems and also keep them at the forefront of research.

  10. Science Forum: RIPOSTE: a framework for improving the design and analysis of laboratory-based research

    Nicholas GD Masca, Elizabeth MA Hensor ... M Dawn Teare
    The RIPOSTE framework has been developed to support early and regular discussions between scientists and statisticians in order to improve the design, conduct and analysis of laboratory studies.
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