For analyzing time-dependent patch-clamp or patch-clamp fluorometry data of ion channels in terms of Markovian models, the superiority of Bayesian filtering with respect to traditional deterministic approaches is demonstrated enabling more reliable quantification of the parameters.
Insecticide-treated net requirements for Africa have been underestimated, but mitigating for inefficiencies in net distributions can produce a cost effective path to universal coverage.
David GT Barrett, Sophie Denève, Christian K Machens
Spiking networks compensate the loss of neurons instantaneously, when restoration of excitatory/inhibitory balance becomes equivalent to restoration of functionality.
David A Knowles, Courtney K Burrows ... Yoav Gilad
Genetic variants that modulate transcriptomic response to doxorubicin in human iPSC-derived cardiomyocytes are predictive of cardiac damage and in vivo sensitivity to anthracycline cardiotoxicity.
The combination of phenotypic measures of antigenic drift and genotypic measures of functional constraint improves the accuracy of long-term seasonal influenza A/H3N2 forecasts.
Deep Learning Artificial Intelligence tools can be developed to accurately identify cell divisions during development and wound repair of epithelial tissue.
Functional brain imaging of subjects while travelling through an alien virtual world reveals how brain regions encode novel environments from scratch thus enabling navigation.