Stem cell derived ventral-spinal cord excitatory neurons self-assemble into a rhythmically bursting neural network whose speed and intercellular coordination are both instructively modulated by cell-type specific interactions with inhibitory neurons.
In vivo recordings in unanesthetized zebrafish larvae show that Purkinje neurons have two stable membrane potential states and that climbing fiber inputs can toggle them to up states during motor episodes.
Spatial accuracy of grid cell firing correlates with the slope of the local field potential theta frequency vs. running speed relationship and integrates velocity signals over past time.
Δ9-Tetrahydrocannabinol impairs motor coordination in mice by inhibiting autophagy in the striatonigral pathway, thus defining a new conceptual view of how cannabis acts in the brain.
Sensory neurons that monitor ambient oxygen control a cascade of responses across multiple layers of interneurons to switch the global state of the nematode C. elegans, reprogramming behavior and gene expression to enable escape from or adaptation to surface exposure.
General principles of the limb segment control for terrestrial locomotion have emerged in evolution and highlight the existence of the laws of biological motion that apply to various animal species.
Novel imaging experiments suggest that fruit flies modify their neural circuitry for walking at slow, medium and fast speeds, and that proprioception is not essential for coordinated walking.