The carbon in lens membrane lipids correlates to the year of birth of an individual, a phenomenon that is unprecedented in the current body of literature.
By performing 15N pulse-labeling of mice, the turnover of hundreds of proteins in eye tissues was measured by mass spectrometry that revealed long-lived metabolic enzymes in the lens.
In studies of gender disparities in academia, increased focus is required on within-group variability and between-group overlap of distributions when interpreting and reporting results.
The primary molecular mechanosensor involved in a physiological process of mechanically induced cell fate differentiation is revealed here for the first time in vivo, highly sensitive and potentially shared by all metazoan epithelia.
