tRNA Q34 modification impacts tyrosine codon decoding and leads to proteome reprogramming in response to antibiotic stress in Vibrio cholerae.

Analysis of genome-wide spatial transcriptomics data reveals cell-type specific subcellular RNA localization, and a subset of genes show significantly high correlation between spatial patterning and 3' UTR length.

Whole-transcriptomic profiling of circulating small extracellular vesicle RNA facilitates the detection of T1a stage colorectal cancer and precancerous advanced adenoma.

Improved chemical, molecular biology, and computational approaches establish an optimized method for accurate and precise quantification of tRNA expression, modifications, and aminoacylation.

The liver microRNA transcriptome of humans with type 2 diabetes and obesity is analyzed for the first time and compared with diet-induced obesity in mice.

Findings identify a new link between oncogenic ß-catenin and exosome biogenesis, which may serve as an important nodal point in the immune escape of hepatocellular carcinoma.

The transcriptional activation of the key developmental timer gene, microRNA lin-4, is driven by the transmembrane transcription factor MYRF following its temporally regulated self-cleavage at the cell membrane.

Serum exosomal sequencing combined with cell and animal experiments indicate that miRNA-199b-5p is a novel miRNA associated with osteoarthritis (OA) and can modulate the onset and progression of the disease.