2,479 results found
    1. Microbiology and Infectious Disease

    Strong inter-population cooperation leads to partner intermixing in microbial communities

    Babak Momeni, Kristen A Brileya ... Wenying Shou
    Simulations and experiments on systems containing two different populations of microorganisms show that interactions that benefit at least one of the populations can lead to communities with stable compositions, and that strong cooperation between two populations can lead to communities in which both populations are mixed together.
    1. Developmental Biology
    2. Neuroscience

    LIN-12/Notch signaling instructs postsynaptic muscle arm development by regulating UNC-40/DCC and MADD-2 in Caenorhabditis elegans

    Pengpeng Li, Kevin M Collins ... Kang Shen
    The Notch signaling pathway has a central role in the formation of the circuit that controls egg-laying in the nematode worm C. elegans.
    1. Plant Biology
    2. Developmental Biology

    Sugar is an endogenous cue for juvenile-to-adult phase transition in plants

    Sha Yu, Li Cao ... Jia-Wei Wang
    Sugar levels in leaves act as a signal for plants to switch from their juvenile to their adult form by regulating the expression of two genes.
    1. Developmental Biology

    A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans

    Huanhu Zhu, Huali Shen ... Min Han
    A lipid acts to promote the development of nematode worm larvae through activation of an enzyme complex called TORC1.
    1. Epidemiology and Global Health

    Predicting mosquito infection from Plasmodium falciparum gametocyte density and estimating the reservoir of infection

    Thomas S Churcher, Teun Bousema ... María-Gloria Basáñez
    Identifying and treating those groups of individuals that are most likely to transmit the malaria parasite to mosquitoes could help to control the spread of the disease.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Fungal effector Ecp6 outcompetes host immune receptor for chitin binding through intrachain LysM dimerization

    Andrea Sánchez-Vallet, Raspudin Saleem-Batcha ... Jeroen R Mesters
    Structural and biochemical analysis of a protein called Ecp6, which is produced by a tomato fungus, reveals how the protein prevents plants from launching an immune response to the chitin in fungal cell walls.
    1. Stem Cells and Regenerative Medicine

    Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species

    Ricardo Antonio Rosselló, Chun-Chun Chen ... Erich D Jarvis
    Cells from vertebrate and invertebrate model systems can be reprogrammed into stem-like cells using mouse genes.
    1. Developmental Biology

    An essential role for maternal control of Nodal signaling

    Pooja Kumari, Patrick C Gilligan ... Karuna Sampath
    Regulation of conserved Nodal factors by a maternal protein ensures that Nodal signaling is repressed until the appropriate time in embryonic development.
  1. Point of View: A fair deal for PhD students and postdocs

    Henry R Bourne
    The relentless expansion that threatens the sustainability of biomedical research in the US takes a heavy toll on young researchers.
    1. Microbiology and Infectious Disease

    A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity

    Alyson Ashe, Tony Bélicard ... Eric A Miska
    Evidence that C. elegans and mammals use homologous versions of the same protein (RIG-1) to activate antiviral defense mechanisms suggests that RIG-1 may have a conserved role in coupling virus recognition to virus destruction.

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