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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Sex-based differences in clearance of chronic Plasmodium falciparum infection

    Jessica Briggs, Noam Teyssier ... Bryan Greenhouse
    Lower malaria prevalence in females does not appear to be due to lower rates of infection but rather due to faster clearance of asymptomatic infections.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1

    Sean R Cuddy, Austin R Schinlever ... Anna R Cliffe
    Herpes simplex virus reactivates from a latent infection when neurons become hyperexcitable in response to an inflammatory cytokine known to be released during fever and stress.
    1. Ecology
    2. Evolutionary Biology

    Effects of domestication on the gut microbiota parallel those of human industrialization

    Aspen T Reese, Katia S Chadaideh ... Rachel N Carmody
    Gut microbial signatures of domestication parallel those of industrialization, implicating shared ecological drivers.
    1. Neuroscience

    Emotional learning retroactively promotes memory integration through rapid neural reactivation and reorganization

    Yannan Zhu, Yimeng Zeng ... Shaozheng Qin
    Emotional learning retroactively promotes memory integration for previously neutral events into episodic memory to foster future event predictions, through rapidly stimulating trial-specific reactivation of overlapping memory traces and reorganization of associated memories among the amygdala, hippocampal, and neocortical circuits.
    1. Developmental Biology
    2. Plant Biology

    Direct ETTIN-auxin interaction controls chromatin states in gynoecium development

    André Kuhn, Sigurd Ramans Harborough ... Lars Østergaard
    Auxin binding to the ETTIN transcription factor disrupts the interaction between ETT and a TPL/TPR co-repressor and subsequently affects chromatin dynamics to ensure proper gynoecium development.
    1. Evolutionary Biology

    Recent shifts in the genomic ancestry of Mexican Americans may alter the genetic architecture of biomedical traits

    Melissa L Spear, Alex Diaz-Papkovich ... Ryan D Hernandez
    Admixture dynamics have recently changed over time in Mexican Americans resulting in an impact on the genetic architecture of phenotypic variation.
    1. Chromosomes and Gene Expression

    Msn2/4 regulate expression of glycolytic enzymes and control transition from quiescence to growth

    Zheng Kuang, Sudarshan Pinglay ... Jef D Boeke
    General stress response factors Msn2 and Msn4 activate glycolytic genes and promote acetyl-CoA accumulation to stimulate growth and proliferation of yeast cells under a nutrient-limiting condition, suggesting the unexpected interrelationship between carbohydrate metabolism and stress response.
    1. Developmental Biology

    Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

    Sapthaswaran Veerapathiran, Cathleen Teh ... Thorsten Wohland
    Wnt3 accomplishes long-range distribution by extracellular diffusion controlled by expression, tissue morphology, interactions with heparan sulfate proteoglycans, and co-receptor-mediated receptor binding to regulate brain development in zebrafish embryos.
    1. Developmental Biology
    2. Evolutionary Biology

    Early maternal loss leads to short- but not long-term effects on diurnal cortisol slopes in wild chimpanzees

    Cédric Girard-Buttoz, Patrick J Tkaczynski ... Catherine Crockford
    Wild chimpanzees contrast to humans since adult male chimpanzees do not exhibit physiological indicators of biological embedding of the stress associated to maternal loss early in life.
    1. Neuroscience

    Detecting changes in dynamic and complex acoustic environments

    Yves Boubenec, Jennifer Lawlor ... Bernhard Englitz
    Psychophysics experiments and EEG recordings reveal that people's performance in detecting unexpected changes in complex auditory scenes can be modeled as a process of sensory evidence accumulation.