6,154 results found
    1. Ecology
    2. Evolutionary Biology

    Dynamics of venom composition across a complex life cycle

    Yaara Y Columbus-Shenkar et al.
    Different developmental stages of a venomous animal (e.g. Nematostella vectensis) with a complex life cycle produce vastly different venoms that can serve in different antagonistic interactions with other species.
    1. Cell Biology

    LINE-1 protein localization and functional dynamics during the cell cycle

    Paolo Mita et al.
    A combination of functional, biochemical and imaging studies show that LINE-1/L1 proteins and mRNA enter the nucleus through mitotic nuclear membrane breakdown, interact with components of the DNA replication fork and mediate retrotransposition during S phase.
    1. Microbiology and Infectious Disease
    2. Stem Cells and Regenerative Medicine

    Stem cell heterogeneity drives the parasitic life cycle of Schistosoma mansoni

    Bo Wang et al.
    Distinct stem cell populations drive larval, somatic, and germline development of the human parasitic flatworm, Schistosoma mansoni.
    1. Cell Biology

    CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets

    Jordina Guillén-Boixet et al.
    CPEB4's switch from translational repressor to activator is regulated during cell cycle by hyperphosphorylation of its intrinsically disordered domain, which controls its phase-separation into RNA-containing liquid-like droplets.
    1. Plant Biology

    Convergent recruitment of TALE homeodomain life cycle regulators to direct sporophyte development in land plants and brown algae

    Alok Arun et al.
    TALE homeodomain transcription factors have been independently recruited to regulate gametophyte to sporophyte transitions in two complex multicellular eukaryotic supergroups, land plants in Archaeplastida and brown algae in Chromalveolata.
    1. Microbiology and Infectious Disease
    2. Genetics and Genomics

    Dissection of the in vitro developmental program of Hammondia hammondi reveals a link between stress sensitivity and life cycle flexibility in Toxoplasma gondii

    Sarah L Sokol et al.
    A derived stress response trait may have contributed to the emergence of a globally dominant and promiscuous parasite.
    1. Developmental Biology
    2. Plant Biology

    Epigenetic reprogramming rewires transcription during the alternation of generations in Arabidopsis

    Michael Borg et al.
    Epigenetic reprogramming of the distinct repressive marks H3K27me3 or H3K9me2 guides the transition between the haploid and diploid life forms that encompass the life cycle of land plants.
    1. Cell Biology
    2. Developmental Biology

    JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress

    Andrea Cosolo et al.
    Tissue damage induces a reversible cell cycle arrest in G2, which promotes survival and mitogenic signals to facilitate tissue regeneration but drives senescence-like phenotypes under chronic stress conditions.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    The life cycle of Drosophila orphan genes

    Nicola Palmieri et al.
    The short lifetime of orphan genes is a major factor explaining the stability of gene number in Drosophila.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Polo-like kinase Cdc5 regulates Spc72 recruitment to spindle pole body in the methylotrophic yeast Ogataea polymorpha

    Hiromi Maekawa et al.
    Cdc5-dependent SPB regulation is linked to delayed cytoplasmic microtubule organization in Ogataea polymorpha.

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