Archaeal histones compact DNA into nucleosome-like particles of varying sizes that contort sporadically and reorient DNA wrapping.

In Thermoplasma acidophilum, an archaeon without histones, a DNA-binding protein acquired from bacteria via horizontal gene transfer mediates histone-like chromatin architecture.

In an unusual complex that is not dissociated by RanGTP alone, Importin-9 sequesters the H2A-H2B core from promiscuous interactions.

Linker histones affect the lineage determination of granulocyte precursor cells via regulation of the transcription factor GATA-2.

Epigenetic restriction of herpes simplex virus occurs in a biphasic manner, in which ATRX maintains viral heterochromatin after an initial phase of chromatin deposition.

The Chd1 motor protein performs two functionally distinct ATP-dependent activities, nucleosome assembly and chromatin remodeling, to generate periodic arrays of nucleosomes.

Two SET-domain containing proteins regulate H3K4me3 by their binding to H3K4me3 through their PHD domain and directly regulate expression of a subset of genes.

The BPTF PHD finger is inhibited from binding the methylated H3 tails in the context of the nucleosome due to their robust interaction with the nucleosomal DNA, which can be modulated by additional histone PTMs.

A normally cytoplasmic deacetylase, Hdac6, localizes to the nucleus in embryonic stem cells, where it regulates the essential Tip60-p400 chromatin remodeling complex.

Sirt3 functions as decrotonylase to regulate histone crotonylation dynamics.