Resetting a young gut microbiota in middle-aged individuals extends life span and slows aging in the naturally short-lived turquoise killifish, a new vertebrate model organism to study how the microbiota affects the aging process.

A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.

Analysis of proteomic data identified protein biomarkers of aging, mortality and aging-related diseases, supporting their use to monitor aging trajectories and identify individuals at higher risk of disease.

Accounting for the impact of smoking, obesity, and alcohol on past mortality trends, we project, compared to common practice, longer individual lifespans and more elderly in society for the future.

A genetic approach indicates that increased active somatic transposon activity can decrease life span and affect some but not all hallmarks of aging.

Among captive chimpanzees, higher agreeableness males and higher openness females survive longer.

In wild bonobos, sibling birth induced a sudden increase in urinary cortisol levels in the older offspring, a physiological response that occurred in all subjects and was independent of their age.

Resident dermal Mφ are programmed locally, independently of bone-marrow monocytes during Staphylococcus aureus infection, leading to transiently increased resistance, which is limited by a decrease in macrophage life span.

Analysis of molecular signatures of lifespan variation across wild yeast isolates revealed how Nature employs environment to modify genotype, gene expression, and metabolome to arrive at different lifespan, while preserving fitness in various ecological niches.