7,935 results found
    1. Neuroscience

    Light-at-night exposure affects brain development through pineal allopregnanolone-dependent mechanisms

    Shogo Haraguchi et al.
    Diurnal variation loss of pineal allopregnanolone synthesis by light-at-night induces pituitary adenylate cyclase-activating polypeptide (PACAP) reduction and transcriptional PACAP repression in the cerebellum, with subsequent Purkinje cell death.
    1. Plant Biology

    Arabidopsis plants perform arithmetic division to prevent starvation at night

    Antonio Scialdone et al.
    Plants implement arithmetic division to optimize use of carbohydrate reserves and thus maintain metabolism and growth at night.
    1. Developmental Biology
    2. Plant Biology

    Integration of light and metabolic signals for stem cell activation at the shoot apical meristem

    Anne Pfeiffer et al.
    TOR kinase guides the transition of plant stem cells from the dormant embryonic state to the active adult state by integrating light and metabolic signals.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria

    Joseph Robert Piechura et al.
    Cyanobacteria cope with both predictable day/night changes and natural fluctuations in light during the day by adjusting the expression dynamics of circadian-clock-controlled genes via a network of transcriptional regulators.
    1. Neuroscience

    Brain Development: The impact of light during the night

    Sophia TC Leung et al.
    Exposing chicks to one hour of light during the night disrupts the releaseof a hormone that is needed by cells in the developing brain to survive.
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    1. Neuroscience

    MagC, magnetic collection of ultrathin sections for volumetric correlative light and electron microscopy

    Thomas Templier
    The augmentation of resin-embedded sample blocks with magnetic resin allows remote actuation of ultrathin sections and deposition at high packing density onto silicon wafers for correlative light and electron microscopy.
    1. Developmental Biology

    The transcription factor Pitx2 positions the embryonic axis and regulates twinning

    Angela Torlopp et al.
    In higher vertebrates, the position of the embryonic axis (the location at which gastrulation starts) is determined by the transcription factor Pitx2, which suggests that the mechanisms of this process, and hence those that regulate twinning, are related to those that set up the left–right axis.
    1. Neuroscience

    Homeostatic regulation of perisynaptic matrix metalloproteinase 9 (MMP9) activity in the amblyopic visual cortex

    Sachiko Murase et al.
    Dark exposure lowers the MMP9 activation threshold, and subsequent light stimulation to an amblyopic eye is sufficient to induce proteolysis at thalamo-cortical synapses in deprived mouse visual cortex.

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