Quantitative analyses of multi-dimensional microscopy datasets with a new Fiji/ImageJ plugin for cell tracking reveal the lineage restrictions and morphogenetic cellular behaviors underlying embryonic limb outgrowth in the direct developing crustacean Parhyale hawaiensis.
Through the interaction between PCP signaling and N-cadherin, oriented cell division and cell rearrangement are coordinated to establish the appropriate tissue architecture critical for limb skeletal morphogenesis.
Selective synapse formation in a retinal motion-sensitive circuit is orchestrated by starburst amacrine cells, which use homotypic interactions to initiate formation of a dendritic scaffold that recruits projections from circuit partners.
Occluding-junctions form a permeability barrier around the hematopoietic niche in Drosophila that controls the production of immune cells in response to infection by shaping the signalling micro-environment produced by the niche.
Regional differences in activator and inhibitor signals alter hair cycle pace across mouse skin and produce unique fur renewal 'landscapes', with fastest renewal on the ventrum and slowest renewal on the ear pinnae.