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Computational modeling and molecular-biological analysis reveal the role of mechanical force and downstream Yap signaling in growth control during the development and regeneration of sensory epithelium of the inner ear.

RNF43 interacts with receptor complexes of the Wnt/PCP signaling and its enzymatic activity results in the reduced cells sensitivity to WNT5A what translates in melanoma into decreased invasive properties and increased response to targeted therapies of this skin cancer.

Wnt3 accomplishes long-range distribution by extracellular diffusion controlled by expression, tissue morphology, interactions with heparan sulfate proteoglycans, and co-receptor-mediated receptor binding to regulate brain development in zebrafish embryos.

Combining global and local force measurements of reconstituted muscle tissue using a new chamber system that is compatible with high-resolution microscopy shows mechanical homeostasis already within a week.

In contrast to growing evidence that juxtracrine signalling accounts for Wnt/Wingless patterning function, Wingless behaves as a released signal in Drosophila renal tubule development, being secreted from the midgut to spread and pattern the proximal tubule.

Distinct metabolic states coupled with differing morphogen levels regulate HC morphology along the tonotopic axis of the developing chick auditory organ.

Single myofiber ATAC-Seq provides assessment of chromatin accessibility of a single myofiber without the confounding effects of other cell types present in skeletal muscle.

Hedgehog signaling plays a role in regulating glia gene expression in planarians, pointing to a candidate ancestral and broadly used role for the Hedgehog pathway.

Identification of a novel source of progenitor cells that form arterial valve leaflets and that, when disrupted, can lead to bicuspid arterial valve, the most common human cardiac malformation.

Results of a zebrafish whole-animal chemical screen for compounds that can rescue ear and myelination defects in an adhesion GPCR (Adgrg6/Gpr126) mutant.