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Poised neuronal genes are repressed by REST and Polycomb in embryonic stem cells independently and via different chromatin modifications.

Developing long bones contain distinct mesenchymal stem-cell populations derived from mesoderm and neural crest, which have specialized functions in skeleton formation and the establishment of the hematopoietic stem-cell niche, respectively.

The patterning of the nephron is driven by a gradient in the activity of β-catenin and further defined by a network of BMP, PTEN and NOTCH signalling.

Single-cell and single-molecule analyses of transient gene expression revealed hitherto unrecognized dynamics in heterochromatin function and defined novel roles for a heterochromatin establishment factor and an understudied sirtuin.

Building on previous work (Randel et al., 2014), a comparison of the visual neuronal circuitry in two Platynereis larvae, made using serial electron microscopic reconstructions, reveals a high level of stereotypy in the synaptic connectivity.

Analysis of a spermiogenesis protein reveals a new chromatin requirement for synchrony between maternal DNA packaged in the egg and sperm-packaged paternal DNA in the first embryonic mitosis in Drosophila melanogaster.

Kinesin-like calmodulin-binding protein integrates microtubules and F-actin to assemble the cytoskeletal configuration needed for trichome formation.