Emily N Truckenbrod, Kristina S Burrack ... Stephen C Jameson
Identification and characterization of the responses of T lymphocytes that are specific for 'self' tissue antigens, revealing the functional limits of immune tolerance.
A massively multiplexed multi-condition screen shows that protein interactomes are larger than previously thought and contain highly dynamic regions that reorganize to drive or respond to cellular changes.
During ES cell differentiation, Yap1 directly regulates apoptosis-related genes like Bcl-2 and Mcl-1 to attenuate apoptosis and promote cell survival to allow for successful cell fate changes.
Maksim Kleverov, Daria Zenkova ... Alexey A Sergushichev
Phantasus democratizes gene expression analysis, offering intuitive and interactive tools that streamline the exploration and analysis of user-provided data and over 96,000 public datasets.
Amanda C Perofsky, John Huddleston ... Cécile Viboud
Antigenic drift in influenza’s major surface proteins, hemagglutinin and neuraminidase, contributes to variability in epidemic magnitude across seasons but is less influential than subtype interference in shaping annual outbreaks.
