Delayed inhibition precisely balances excitation from arbitrary combinations of CA3 neurons and controls the gain of CA1 output by reducing inhibitory delay with increasing excitation.

Mathematical and experimental analyses suggest that despite their complex architectures, multiple metazoan signaling pathways act in physiological contexts as linear signal transmitters.

Many V1 double-opponent cells integrate light information across their receptive fields as linearly as simple cells do.

Cerebellar Purkinje cells represent movements via bidirectional linear changes in spike rate, and activity from single cells is sufficient to reconstruct kinematic changes during bouts of free whisking.

Responses to odour mixtures are more discriminable in awake, behaving mice due to a combination of dampened responses keeping responses in the linear range and pattern decorrelation, with these two mechanisms operating on different timescales.

A combination of electrophysiology and quantitative modeling shows that subtle changes in input due to adaptation in cone phototransduction control the linearity or nonlinearity of how ganglion cells integrate spatial inputs.

Despite employing diverse molecular mechanisms, many different cell signaling systems avoid losing information by transmitting it in a linear manner.

Loading and linear translocation of condensin dosage compensation along the X-chromosomes create the loop-anchored topologically associating domains detected by Hi-C.

Multi-electrode recordings and modeling are combined to reveal the transformations of signals from cones to bipolar cells and then to ganglion cells within the primate retina.

Novel stimulation patterns and large-scale neural activity recording show that an input-specific supra-linear summation synthesizes a sparse, but comprehensive code of tactile and visual stimuli in the sensory cortex.