19 results found
    1. Microbiology and Infectious Disease

    Inhibiting host-protein deposition on urinary catheters reduces associated urinary tract infections

    Marissa Jeme Andersen, ChunKi Fong ... Ana L Flores-Mireles
    The use of liquid-infused catheters results in significant reduction of bladder and catheter colonization, systemic dissemination, and bladder inflammation in a clinically relevant mouse model of CAUTI by targeting host-protein deposition on the urinary catheter.
    1. Physics of Living Systems

    A multiphase theory for spreading microbial swarms and films

    Siddarth Srinivasan, C Nadir Kaplan, L Mahadevan
    A multiphase hydrodynamic theory reveals that the dynamics of colony expansion in microbial swarms and biofilms are limited by the constraints of water and nutrient availability.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Protein gradients on the nucleoid position the carbon-fixing organelles of cyanobacteria

    Joshua S MacCready, Pusparanee Hakim ... Daniel C Ducat
    Carboxysomes, the carbon-fixation machinery of cyanobacteria, are equidistantly-positioned by dynamic gradients of the protein McdA on the nucleoid that emerge through interaction with a previously unidentified carboxysome factor, McdB.
    1. Microbiology and Infectious Disease

    Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress

    Suneeta Chimalapati, Marcela de Souza Santos ... Kim Orth
    Considering the course of a pathogen's evolution, there appears to be interplay between secretion systems, providing unique, synergistic mechanisms to support a successful lifestyle for possibly pathogenesis, symbiosis and/or parasitosis.
    1. Physics of Living Systems

    Self-organized canals enable long-range directed material transport in bacterial communities

    Ye Li, Shiqi Liu ... Yilin Wu
    Mechanochemical coupling between interfacial force and biosurfactant kinetics can coordinate large-scale material transport in primitive life forms, suggesting a new principle to engineer self-organized microbial communities.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins

    Anna Caballe, Dawn M Wenzel ... Juan Martin-Serrano
    ULK3 is a kinase in the abscission checkpoint that temporarily inactivates ESCRT-III proteins via phosphorylation, which is required to delay cytokinesis in response to defects in mitosis.
    1. Cell Biology

    Consequences of PDGFRα+ fibroblast reduction in adult murine hearts

    Jill T Kuwabara, Akitoshi Hara ... Michelle D Tallquist
    Cardiac fibroblast reduction is well-tolerated and demonstrates beneficial outcomes after heart injury.
    1. Cell Biology

    A robust method for particulate detection of a genetic tag for 3D electron microscopy

    James Rae, Charles Ferguson ... Robert G Parton
    Development of a new system for gold particle detection of a genetic tag for electron microscopy.
    1. Ecology

    Food-washing monkeys recognize the law of diminishing returns

    Jessica E. Rosien, Luke D. Fannin ... Amanda Tan
    Not revised
    Reviewed Preprint v1
    1. Medicine

    Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis

    Sindre Lee-Ødegård, Marit Hjorth ... Kåre Inge Birkeland
    Long-term physical exercise had a substantial effect on the plasma proteome, identifying novel exerkines and suggesting CD300LG as a potential link to insulin sensitivity.

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