A single amino acid change in a neuronal ion channel called KCNQ2 blocks ion flow, prevents protein localization on axons, and results in severe epilepsy and slowed neurological development.

Contrasting climatic dependencies of macrofauna and microorganisms generate similar whole-community decomposition rates across a precipitation gradient, plausibly resolving the longstanding puzzle of why arid-land litter decomposition is decoupled from precipitation.

An inoculation experiment shows phyllosphere microbiome plays an important role in invader Ageratina adenophora population establishment by killing seedlings at very early growth stage.

The enduring impacts of early-life seizures on cognition and behavior are not attributed to neuronal loss but to disrupted hippocampus-prefrontal cortex network dynamics, heightened neuroinflammation, and altered dopaminergic transmission.

The application of real-time genomics by long-read nanopore sequencing to environmental samples creates a new trajectory for non-invasive genomics-based monitoring of critically endangered wildlife.

Cylicin 1 and Cylicin 2 are essential components of the sperm perinuclear theca and their loss results in impaired spermiogenesis and thus in infertility in mice and men.

Frontal cortical circuit alterations and cognitive deficits identified in mouse genetic models are reversed by chemogenetic or optogenetic stimulation of the mesocortical dopamine circuit in an adolescent period.

Impairing TDP-43 RNA-binding capacity through a single acetylation-mimic mutation alters TDP-43 function and recapitulates biochemical, molecular, and behavioral features of sporadic TDP-43 proteinopathies, thus providing opportunities for new research into pathogenic mechanisms and therapeutic interventions.