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    1. Ecology
    2. Evolutionary Biology

    Dynamics of venom composition across a complex life cycle

    Yaara Y Columbus-Shenkar et al.
    Different developmental stages of a venomous animal (e.g. Nematostella vectensis) with a complex life cycle produce vastly different venoms that can serve in different antagonistic interactions with other species.
    1. Computational and Systems Biology
    2. Neuroscience

    Antagonism in olfactory receptor neurons and its implications for the perception of odor mixtures

    Gautam Reddy et al.
    Computational and theoretical analyses offer novel and unexpected insight into how complex, naturally occurring odor mixtures are parsed and normalized at the very first stage of olfaction.
    1. Microbiology and Infectious Disease

    Changes in the genetic requirements for microbial interactions with increasing community complexity

    Manon Morin et al.
    Analysis of the global genetic requirements and gene expression changes in E. coli in the presence of a simple microbiome revealed pairwise and higher-order interactions, and underlying molecular mechanisms.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Large protein organelles form a new iron sequestration system with high storage capacity

    Tobias W Giessen et al.
    An alternative iron storage system based on a 9.6 megadalton microbial protein compartment is able to sequester and store large amounts of iron.
    1. Neuroscience

    Capturing the temporal evolution of choice across prefrontal cortex

    Laurence T Hunt et al.
    Experiments in macaques and humans reveal time-varying changes in prefrontal cortex activity that occur during decisions based on costs and benefits.
    1. Neuroscience

    Creating and controlling visual environments using BonVision

    Gonçalo Lopes et al.
    BonVision is an open-source software for real-time rendering and control of 2D and 3D visual environments that also enables easy replication of experiments.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication

    Jeziel Dener Damasceno et al.
    Duplication of Leishmania chromosomes combines S-phase DNA replication initiated at a single internal region with subtelomeric DNA replication detectable outside S-phase, potentially explaining genome plasticity in this important parasite.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Delayed antibiotic exposure induces population collapse in enterococcal communities with drug-resistant subpopulations

    Kelsey M Hallinen et al.
    Collapse of bacterial communities containing antibiotic-resistant and susceptible cells can be driven by increased population size or delayed drug exposure.
    1. Structural Biology and Molecular Biophysics

    Large-scale state-dependent membrane remodeling by a transporter protein

    Wenchang Zhou et al.
    The conformational mechanism of a transporter protein is found to have profound and energetically costly effects on the morphology of the surrounding membrane.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The autophagic membrane tether ATG2A transfers lipids between membranes

    Shintaro Maeda et al.
    The autophagy protein ATG2A tethers membranes and transfers lipids between them, suggesting that autophagosome membranes grow upon the acquisition of lipids from the ER through the ATG2A bridge.