Mean kurtosis brain maps, derived from a sub-diffusion model with a novel clinically feasible two-diffusion-time acquisition, exhibit superior tissue contrast compared to the traditional diffusional kurtosis imaging (DKI).

An in vivo reporter of TGFb signaling in zebrafish reveals that melanoma cells undergoing chronic TGFb signaling up-regulate extracellular matrix genes, down-regulate IFN, and are preferentially phagocytosed by macrophages compared to non-TGFb responsive melanoma cells.

Based on benchmarking various methods and analyzing multiple real scRNA-seq datasets, a computational platform/workflow and a set of tips for best practices are developed for analyzing causal interactions or relationships in single cells.

Gene sharing through different isoforms can precede the formation of independent genes.

A single-nucleus atlas of bone repair uncovers the trajectories of periosteal skeletal stem/progenitor cells in response to fracture and identifies injury-induced fibrogenic cells as intermediate osteochondroprogenitors and key paracrine regulators.

Secretion and fibrillogenesis of collagen-I are separately controlled molecular pathways in the fibroblast, where surprisingly endocytic recycling is required for fibril formation and is increased in fibrotic fibroblasts.

Tumor-induced myeloid-derived suppressor cells exert systemic suppression of adaptive immunity by limiting L-selectin-directed trafficking of T cells at vascular checkpoints in lymph nodes.

Inhibition of microRNA-203 by oncogenic HRas mutations promotes skin cancer initiation.

Structurally divergent bacterial-like mechanosensitive channels control multiple cellular functions in protozoan parasites.