In this episode we hear about the cocktail party effect, the role of psuedogene RNA in the immune response, the genetic origins of a common form of blindness, the flu vaccine, and the origins of schistosomiasis.
Eukaryotic translation elongation factor 1A1 controls the process of heat shock response, from transcriptional activation of the HSP70 gene, to HSP70 mRNA stabilization, nuclear export, and translation.
The genome of Thermovibrio ammonificans encodes ancestral pathways (e.g., hydrogen oxidation) and more recently acquired ones (e.g., nitrate reduction) and a hybrid pathway for CO2 fixation.
Single-cell transcriptional profiling reveals distinct neuronal subtypes of the lateral habenula differentially target downstream neuronal subtypes in the ventral tegmental area and dorsal raphe nucleus.
Mitochondria can trigger massive endocytosis by releasing coenzyme A into the cytoplasm and thereby promoting the addition of fatty acids to surface membrane proteins.
Parenchymal astrocytes are quiescent neural stem cells whose neurogenic potential can be unleashed by targeted manipulations guided by single-cell RNA sequencing data.
The transcriptomic profiles of the constituent monotherapies of synergistic drug pairs tend to be correlated and result in novel gene expression in the combinations.
In medaka fish, galanin-expressing neurons in the medial preoptic area occur nearly exclusively in males and mediate androgen-dependent male–male aggressive chases.