Patterns of coordinated activity in the basal ganglia predict how much force we will use to grip objects, suggesting that individuals with paralysis may ultimately be able to use these signals to control graded responses in robotic devices.
Multivariate data decomposition applied to local field potentials recorded from the primate amygdala revealed simultaneously active and functionally distinct networks, defined by anatomical boundaries between the nuclei.
Cerebellar Purkinje neurons use a multiplexed simple spike code combining synchrony/spike time and firing rate, with each component encoding distinct information about movements such as motion onset timing and kinematics.
Dopaminergic medication has differential effects on the discovered electrophysiological networks, which could be used to develop new electrical and pharmacological interventions in Parkinson’s disease.
In the visual system, three rules guide the thalamocortical connectivity of cortical fast-spike interneurons and are key to understand the potent and broadly tuned feed-forward inhibition that they generate.