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Using a yeast model of quiescence, it was demonstrated that dramatic changes in local chromatin fiber folding can occur under physiological conditions to regulate cellular processes.

In situ structural analysis of bacterial flagellar motor in the Lyme disease spirochete reveals novel conformational change driven by proton motive force.

Human hippocampal cornu ammonis 3 damage impairs both recent and remote autobiographical episodic memory, and disrupts functional integration in medial temporal lobe subsystem regions of the default network.

Brain-heart interactions under the processing of auditory irregularities could help to distinguish whether a patient is in a vegetative state or in a minimally conscious state.

Multiple axonal guidance receptors control the local and selective translation of mRNAs by binding to ribosomes, specific mRNAs and RNA-binding proteins.

Computational analysis reveals that additive summary statistics from genome-wide association studies can provide evidence of non-additive heritability in complex traits.

In astrocytes, there exists an intrinsic spatial threshold of subcellular calcium levels that triggers an astrocyte calcium surge throughout the cell, demonstrating cellular astrocyte calcium integration of time and space.

A genetic mapping study in more than 1000 yeast individuals reveals the complexity of trans-acting genetic influences on transcriptome variation in unprecedented depth and detail.

CTP and centromere-like parS-DNA act synergistically and catalytically to activate ParB, which remains activated after leaving parS to tune ParA–ParB and ParB–ParB interaction dynamics for robust ParABS-mediated F-plasmid DNA segregation.

Lung interstitial macrophages are strategically positioned underneath the bronchial airway epithelium and enriched at airway bifurcations for immunosurveillance of the conducting airway lumen and the initiation of adaptive immune responses.