563 results found
    1. Neuroscience

    A bidirectional network for appetite control in larval zebrafish

    Caroline Lei Wee et al.
    Brain imaging and behavioral analysis reveal two opposing states of hunger, represented by anti-correlated lateral and caudal hypothalamic dynamics that are important for the homeostatic control of feeding in zebrafish.
    1. Genetics and Genomics
    2. Neuroscience

    Dissection of central clock function in Drosophila through cell-specific CRISPR-mediated clock gene disruption

    Rebecca Delventhal et al.
    Through novel, cell-specific CRISPR tools to disrupt molecular clock genes, it was revealed that circadian rhythms are coordinated through a network, rather than by the clock of 'master regulatory' neurons.
    1. Neuroscience

    Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity

    Matthias Schlichting et al.
    Network silencing experiments and cell-specific CRISPR/Cas9 knockouts suggest that network communication is necessary for generating robust rhythms within the clock neuron network.
    1. Neuroscience

    In vivo functional diversity of midbrain dopamine neurons within identified axonal projections

    Navid Farassat et al.
    Midbrain dopamine neurons function according to their axonal projections in the intact brain.
    1. Developmental Biology

    N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

    Elif Kon et al.
    FGFRs regulate multipolar cortical neuron orientation and the morphological change into bipolar cells in vivo under the control of N-Cadherin and the extracellular matrix protein Reelin.
    1. Microbiology and Infectious Disease

    Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of Toxoplasma gondii

    Alex Hunt et al.
    Partially overlapping functions of a limited subset of actin binding proteins allow the parasite Toxoplasma gondii to achieve actin regulation required for complex cellular processes.
    1. Neuroscience

    Motor cortex signals for each arm are mixed across hemispheres and neurons yet partitioned within the population response

    Katherine Cora Ames, Mark M Churchland
    Neurons in motor cortex contain information about each arm, but these signals are separated into different dimensions, allowing separate control of each arm.
    1. Structural Biology and Molecular Biophysics

    Kinesin and dynein use distinct mechanisms to bypass obstacles

    Luke S Ferro et al.
    Dynein bypasses obstacles on microtubules more efficiently than single kinesin, and kinesins overcome this limitation when transporting intracellular cargos in teams.
    1. Neuroscience

    Pretectal neurons control hunting behaviour

    Paride Antinucci et al.
    A discrete population of genetically accessible pretectal neurons controls visually guided hunting behaviour in larval zebrafish.
    1. Neuroscience

    A primal role for the vestibular sense in the development of coordinated locomotion

    David E Ehrlich, David Schoppik
    Zebrafish use their sense of gravity and their cerebellum to coordinate the fin and body movements that, as they develop, allow them to better maintain balance as they climb.

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