3,185 results found
    1. Plant Biology

    Testing the Münch hypothesis of long distance phloem transport in plants

    Michael Knoblauch et al.
    Measurements of physiological and geometrical parameters of the sieve tube system in Ipomoea nil provide strong support for pressure driven mass flow.
    1. Developmental Biology

    Cytoneme-mediated cell-cell contacts for Hedgehog reception

    Laura González-Méndez et al.
    Direct interaction between Hedgehog-sending and Hedgehog-receiving cytonemes is a fundamental mechanism for morphogen transfer and gradient establishment.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A phylogenetic transform enhances analysis of compositional microbiota data

    Justin D Silverman et al.
    The PhILR transform uses an evolutionary model to overcome statistical challenges associated with microbiota surveys.
    1. Plant Biology

    Long Distance Transport: Under pressure

    Ulrich Z Hammes
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    1. Physics of Living Systems

    A minimal self-organisation model of the Golgi apparatus

    Quentin Vagne et al.
    An unbiased model for the self-organisation of the Golgi apparatus displays either anterograde vesicular transport or cisternal maturation depending on ratios of budding, fusion and biochemical conversion rates.
    1. Cell Biology
    2. Computational and Systems Biology

    Deciphering anomalous heterogeneous intracellular transport with neural networks

    Daniel Han et al.
    Direct estimation of the Hurst exponent shows that endosomes and lysosomes reside in regimes of persistent and anti-persistent motion with heavy-tailed residence time distributions and motion correlated with endocytic function.
    1. Cell Biology
    2. Physics of Living Systems

    A physical mechanism of TANGO1-mediated bulky cargo export

    Ishier Raote et al.
    TANGO1 functions as a linactant filament to stabilize shallow COPII-coated buds, and after which membrane tension regulation, possibly mediated by TANGO1-controlled membrane fusion, facilitates bud elongation for procollagen export.
    1. Ecology
    2. Physics of Living Systems

    Ant collective cognition allows for efficient navigation through disordered environments

    Aviram Gelblum et al.
    When real ants confront the classical 'Ant-in-a-labyrinth' physics problem where a random walker traverses a percolated environment, they employ active extended sensing and collective cognition to outperform passive physical solutions.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Proofreading through spatial gradients

    Vahe Galstyan et al.
    Theoretical study shows how enzymes can achieve substrate proofreading by taking advantage of existing molecular gradients in the cell while not being endowed with structural features typically required for proofreading.
    1. Cell Biology
    2. Neuroscience

    Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

    Junjun Zhao et al.
    Two homologous kinesin motors, KIF5A and KIF5B, have distinct functions in dendritic spine morphogenesis, and KIF5B plays a role in synaptic plasticity and memory.

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