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    1. Cell Biology
    2. Microbiology and Infectious Disease

    Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth

    Deniz Cizmeci, Giuseppe Lofano ... Boris Julg
    Extended somatic hypermutation and clonal evolution associated with antibody neutralization breath in HIV controllers with low plasma viral loads provide promise for HIV vaccine development.
    1. Neuroscience

    Behavioral evidence for memory replay of video episodes in the macaque

    Shuzhen Zuo, Lei Wang ... Sze Chai Kwok
    Macaque monkeys temporally compress past experiences and use a forward-replay mechanism during judgment of temporal-order between episodes.
    1. Computational and Systems Biology

    Meta-Research: How parenthood contributes to gender gaps in academia

    Xiang Zheng, Haimiao Yuan, Chaoqun Ni
    Gender gaps in academic achievement are in fact "parenthood gender gaps", with mothers experiencing higher levels of work-family conflict, and receiving lower levels of partner support, than fathers.
    1. Developmental Biology
    2. Neuroscience

    Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

    Ryoji Amamoto, Grace K Wallick, Constance L Cepko
    Retinoic acid signaling from Muller glia is necessary for cone photoreceptor survival in the peripheral retina and is sufficient to promote cone survival in the central retina during retinal degeneration.
    1. Neuroscience

    The expression of established cognitive brain states stabilizes with working memory development

    David Florentino Montez, Finnegan J Calabro, Beatriz Luna
    The excessive behavioral variability associated with adolescence is the result of greater instability of widespread or global gain signals which produces greater variability in the amplitude of expression of whole-brain states of task-related activity.
    1. Computational and Systems Biology
    2. Neuroscience

    Principles for coding associative memories in a compact neural network

    Christian Pritz, Eyal Itskovits ... Alon Zaslaver
    A compact neural network can form various associative memories that are encoded in a distributed manner, where each neuron stores different components of the memory.
    1. Neuroscience

    Value construction through sequential sampling explains serial dependencies in decision making

    Ariel Zylberberg, Akram Bakkour ... Michael N Shadlen
    The subjective value of choice options changes during deliberation, and accounting for these changes improves predictions of choices, response times, and BOLD fMRI activity.
    1. Computational and Systems Biology

    Recurrent neural networks enable design of multifunctional synthetic human gut microbiome dynamics

    Mayank Baranwal, Ryan L Clark ... Ophelia S Venturelli
    Recurrent neural network models enable prediction and design of health-relevant metabolite dynamics in synthetic human gut communities.
    1. Neuroscience

    Motor context dominates output from purkinje cell functional regions during reflexive visuomotor behaviours

    Laura D Knogler, Andreas M Kist, Ruben Portugues
    Purkinje cells of the cerebellum, a conserved vertebrate brain region important for sensorimotor integration, receive sensory and motor information from distinct input streams and are functionally clustered into modules reflecting the larval zebrafish's behavioral repertoire.
    1. Neuroscience

    EEG-fMRI in awake rat and whole-brain simulations show decreased brain responsiveness to sensory stimulations during absence seizures

    Petteri Stenroos, Isabelle Guillemain ... Emmanuel L Barbier
    Rats with absence epilepsy exhibit hindered and restricted sensory processing during ongoing seizures, as demonstrated by functional magnetic resonance imaging and mean-field simulation studies.