Rhythmic centrifugal waves of auxin traveling through the tissue provides high definition positional information to cells that is not only spatial but also temporal.

Combined TMS-EEG can be used to further elucidate the mechanisms for pain perception and to discover biomarkers for the development of chronic pain.

Interconnected ventral tegmental area and medial prefrontal cortex circuits causally link dopamine dynamics, aversive learning, and the effects of a promising rapidly acting antidepressant ketamine.

Activation of Wnt/β-catenin signaling in endothelial progenitors derived from human pluripotent stem cells partially induces the specialized blood–brain barrier phenotype while the same treatment in matured endothelial cells is less efficacious.

Maturation of cortical network dynamics is characterized by a nadir that signals the shift from local, loosely correlated, prominently sensory-driven patterns to internally organized, spatially distributed, and temporally precise activity.

Novel components in the pathway from malignant hyperthermia to diabetes include promotion of a kinase that impedes glycogen synthesis, increased lysis of junctophilin1 and gene regulatory actions by a junctophilin fragment, surprisingly predicted to oppose the effects of elevated calcium.

The enduring impacts of early-life seizures on cognition and behavior are not attributed to neuronal loss but to disrupted hippocampus-prefrontal cortex network dynamics, heightened neuroinflammation, and altered dopaminergic transmission.

Building on previous work (Faull et al, 2016), it shown that the different connectivity profiles of the individual columns of the human periaqueductal gray support their proposed roles in human threat behaviours, such as freezing or fight/flight.

Newly recovered lumbar vertebrae belonging to Malapa Hominin 2, an adult female of the fossil hominin species Australopithecus sediba, demonstrate that this individual was adapted to upright posture and bipedal locomotion but also had adaptations for climbing in trees.

Single-cell sequencing combined with in situ hybridizations reveal dynamic patterns of differentially expressed genes throughout the ventricular and subventricular zone of the embryonic mouse brain, which likely play important roles in cell fate determination.