5,019 results found
    1. Neuroscience

    A suppression hierarchy among competing motor programs drives sequential grooming in Drosophila

    Andrew M Seeds et al.
    Gaining genetic control over neural modules that drive the grooming of each Drosophila body part reveals how mechanisms for selecting among competing behavioral choices are used to generate sequences of actions.
    1. Developmental Biology
    2. Immunology and Inflammation

    Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus

    Federico Andrea Moretti et al.
    T cell progenitor homing into the thymus requires kindlin-3 to stabilize their adhesion to vascular integrin ligands when blood flow velocities and shear rates increase during development.
    1. Ecology

    Carbon recovery dynamics following disturbance by selective logging in Amazonian forests

    Camille Piponiot et al.
    Carbon recovery in Amazonian forests disturbed by selective logging is higher in the Guiana Shield and in the west, and is mainly shaped by the carbon gain of trees that survived the disturbance.
    1. Computational and Systems Biology
    2. Neuroscience

    Automated analysis of long-term grooming behavior in Drosophila using a k-nearest neighbors classifier

    Bing Qiao et al.
    Drosophila grooming is driven by two internal programs.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Structural evidence for Scc4-dependent localization of cohesin loading

    Stephen M Hinshaw et al.
    Cohesin loading at centromeres depends on a conserved surface cluster of amino-acid residues on the cohesin loading protein, Scc4.
    1. Neuroscience

    A neural command circuit for grooming movement control

    Stefanie Hampel et al.
    The identification of a neural circuit that drives a specific grooming movement in Drosophila reveals that it may also control movement parameters, such as duration.
    1. Neuroscience

    Simultaneous activation of parallel sensory pathways promotes a grooming sequence in Drosophila

    Stefanie Hampel et al.
    A grooming sequence is produced by a neural architecture that readies different movements simultaneously, and a mechanism where prioritized suppression between the movements determines their sequential performance.
    1. Chromosomes and Gene Expression

    MCM2–7-dependent cohesin loading during S phase promotes sister-chromatid cohesion

    Ge Zheng et al.
    Systematic analyses of DNA replication machinery components in human cells reveal a requirement of MCM-dependent de novo loading or mobilization of cohesin at replication forks in establishing sister-chromatid cohesion.
    1. Chromosomes and Gene Expression

    Scc2/Nipbl hops between chromosomal cohesin rings after loading

    James Rhodes et al.
    The cohesin loading factor Scc2/Nipbl interacts frequently with cohesin after the loading reaction in a manner consistent with a role in stimulating loop extrusion.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Viral hijacking of a replicative helicase loader and its implications for helicase loading control and phage replication

    Iris V Hood, James M Berger
    A phage-encoded protein inhibits a bacterial replicative helicase loading factor by exploiting an internal site that auto-regulates loader self-assembly and ATPase activity.

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