1,251 results found
    1. Medicine
    2. Neuroscience

    mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

    Philip Stavrides, Chris N Goulbourne ... Dun-Sheng Yang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics

    fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans

    Angela M Tuckowski, Safa Beydoun ... Scott F Leiser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Solid
    1. Microbiology and Infectious Disease

    Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody

    Manuela C Aguirre-Botero, Olga Pacios ... Rogerio Amino
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Altering the redox status of Chlamydia trachomatis directly impacts its developmental cycle progression

    Vandana Singh, Scot P Ouellette
    Differentiation of the pathogenic bacterium, Chlamydia trachomatis, from its non-infectious to infectious form is linked to the redox state of the organism.
    1. Medicine

    Exploration of the metabolomic mechanisms of postmenopausal hypertension induced by low estrogen state

    Yao Li, Hui Xin ... Wei Zhang
    Low estrogen levels in postmenopausal hypertension are linked to metabolic reprogramming and aortic tissue changes, with L-alpha-aminobutyric acid emerging as a potential protective biomarker.
    1. Cell Biology

    Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

    Joan Chang, Adam Pickard ... Karl E Kadler
    Secretion and fibrillogenesis of collagen-I are separately controlled molecular pathways in the fibroblast, where surprisingly endocytic recycling is required for fibril formation and is increased in fibrotic fibroblasts.
    1. Cell Biology

    Atlas of Fshr expression from novel reporter mice

    Hongqian Chen, Hui-Qing Fang ... Peng Liu
    Exploiting the power of the Fshr reporter, the first comprehensive genetic record of the spatial distribution of FSHR expression offers prospects for extensive exploration of FSH-FSHR biology.
    1. Developmental Biology

    Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women

    Emily Delgouffe, Samuel Madureira Silva ... Ellen Goossens
    Gender-affirming hormone therapy in trans women leads to a loss of mature characteristics in the spermatogonial stem cell niche, causes spermatogenic arrest, and triggers fibrotic processes.
    1. Microbiology and Infectious Disease

    Prophage regulation of Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta

    Ojas Natarajan, Susanne L Gibboney ... Larry J Dishaw
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    p53 engagement is a hallmark of an unfolded protein response in the nucleus of mammalian cells

    Joseph H Park, Thomas J Wandless
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete

Refine your results by:

Type
Research categories