Dylan H Morris, Velislava N Petrova ... Colin A Russell
Despite the virus' error prone polymerase, influenza virus antigenic evolution is rare, even in previously immune hosts, virus replication occurs before producing new antibodies.
A genetic oscillator composed of NHR-23 and let-7 family of microRNAs links the molting cycle timer and the heterochronic pathway to regulate the pace of molting in C. elegans and ensure that worms molt only four times.
Chih-Chieh (Jay) Yu, Nicholas C Barry ... Edward S Boyden
Fixed, intact animals of C. elegans can be physically expanded with high isotropy, to enable super-resolved imaging of general proteins and nucleic acids throughout the organism, on conventional microscopes.
The super-resolution fluorescence microscopy approach polarization PALM (p-PALM) reveals that macromolecular crowding and inhomogeneity within nuclear pores generate a structurally and dynamically complex permeability barrier.
Sven Dorkenwald, Nicholas L Turner ... H Sebastian Seung
Sizes of synapses between layer 2/3 pyramidal cells in mouse primary visual cortex are well modeled by the sum of a binary variable and an analog variable drawn from a log-normal distribution.