RBM7 functions as a novel regulator of MFGE8 alternative splicing and p65 phosphorylation to counteract the metastatic potential of breast cancer, offering novel mechanistic insights into how abnormal splicing contributes to tumor aggressiveness.
The endosomal apparatus of African trypanosomes consists a continuous membrane system with functional subdomains rather than distinct compartments for early, late, and recycling endosomes.
Nora C Brown, Benjamin Gordon ... Mariana Federica Wolfner
A functional genetics approach reveals a novel role for odorant binding proteins in post-mating processes, with complex mechanisms of evolutionary change across closely related insect species.
Genome-intact HIV-1 proviruses were detected in autopsy samples from the brain of ART-treated persons living with HIV, indicating that the virus can persist in the central nervous system.
Intercellular interactions between fibrocytes and CD8+ T lymphocytes promote inflammation through a pathophysiological positive feedback loop in bronchi of patients with chronic obstructive pulmonary disease (COPD).
