In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

Significant technical improvement in single-nucleus RNA-seq reveals distinct adipocyte subpopulations that respond differently to obesity, including those undergoing adaptive healthy expansion and others displaying severe dysfunction.

Systems analysis of antibody repertoires reveals that strong humoral responses lead to extensive B-cell overlap across multiple lymphoid organs, indicating physiological axes of B-cell migration and a direct correlation with antigen specificity.

The water channel AQP4 contributes to a tonic water outflow from brain astrocytes, thereby modulating their volume dynamics and the ambient water homeostasis.

A comprehensive molecular characterization of Schlemm’s canal cells to date provides a wealth of molecular details.