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Monounsaturated fatty acids protect against DKD by enhancing membrane fluidity and decreasing ER lipid bilayer stress in renal proximal tubules.

A road to modulators of the kinase activity and the non-enzymatic functions of Src and IDO1 at once.

In vitro fertilization-conceived murine embryos show evidence of oxidative and metabolic stress with alteration in lactic acid metabolism.

Sphinganine-1-phosphate (SA1P) is linked to paclitaxel-induced peripheral neuropathy, offering a potential target for reducing this severe side effect of paclitaxel treatment.

DIP2 is a conserved protein across fungi and animals that regulates specific diacylglycerol pools by diverting them to storage lipid biosynthesis to enable cellular homeostasis and adaptations.

LPCAT3 incorporates arachidonic acid into membrane phospholipids, which promotes lipoprotein assembly by enabling triacylgylcerols to cluster in the membrane.

Under normal nutritional conditions, G-protein coupled receptors can control autophagy by regulating the degradation of key autophagic regulator Atg14L through ZBTB16-mediated ubiquitination and proteasome degradation.

Impairment of the autocrine S1PR1-Gi signaling on HEVs results in high-endothelial cell apoptosis, reduced CCL21-secretion from HEVs, and cessation of HEV-DC interactions and lymphocyte immigration across the high-endothelial barrier.

Identification of two arbuscular mycorrhiza-specific lipid biosynthesis mutants and fatty acid transfer experiments reveal that host plant lipids are transferred to symbiotic fungi and needed for their development.

Membrane potential adjustment required for growth plate chondrocytic signal conversion from cGMP to Ca²⁺ influx toward long bone outgrowth.