114 results found
    1. Neuroscience

    Macro-scale patterns in functional connectivity associated with ongoing thought patterns and dispositional traits

    Samyogita Hardikar, Bronte Mckeown ... Jonathan Smallwood
    Interactions between attention systems and the default mode network are linked to individual differences in trait and state-level experience and cognition.
    1. Neuroscience

    Concurrent decoding of distinct neurophysiological fingerprints of tremor and bradykinesia in Parkinson’s disease

    Peter M Lauro, Shane Lee ... Wael F Asaad
    Motor signs of Parkinson’s disease such as tremor and bradykinesia are independently expressed and exhibit distinct signatures of neural activity that can independently decoded from subthalamic and cortical recordings using interpretable machine learning.
    1. Neuroscience

    Cross-movie prediction of individualized functional topography

    Guo Jiahui, Ma Feilong ... M Ida Gobbini
    A computational approach based on connectivity hyperalignment can estimate individualized functional topography with high fidelity across movie contents, scanners, protocols, and languages.
    1. Genetics and Genomics
    2. Neuroscience

    Integrated transcriptomic and neuroimaging brain model decodes biological mechanisms in aging and Alzheimer’s disease

    Quadri Adewale, Ahmed F Khan ... Alzheimer's Disease Neuroimaging Initiative
    Identification of causal genes and their effects on other biological determinants untangles the complexities of aging and Alzheimer's and can facilitate drug discovery for sustaining healthy aging and treating Alzheimer's.
    1. Neuroscience

    Non-rapid eye movement sleep and wake neurophysiology in schizophrenia

    Nataliia Kozhemiako, Jun Wang ... Jen Q Pan
    Multiple non-redundant features of non-rapid eye movement sleep are altered in schizophrenia and largely independent of waking electrophysiological abnormalities, supporting the promise of neuropsychiatric disease biomarkers based on a precise dissection of the sleep.
    1. Computational and Systems Biology
    2. Neuroscience

    Neuronal timescales are functionally dynamic and shaped by cortical microarchitecture

    Richard Gao, Ruud L van den Brink ... Bradley Voytek
    Invasive electrophysiological recording measures neuronal transmembrane current timescales across human cortex, which lengthens from sensory to association regions, follows variations in ion channel expressions, and alters with behavior and aging.
    1. Neuroscience

    Altered topology of neural circuits in congenital prosopagnosia

    Gideon Rosenthal, Michal Tanzer ... Galia Avidan
    An innovative inter-subject stimulus-locked brain activation approach uncovers marked topological differences in a brain network of higher-order visual regions in individuals with a congenital impairment in face recognition compared with controls.
    1. Computational and Systems Biology
    2. Neuroscience

    Differences in topological progression profile among neurodegenerative diseases from imaging data

    Sara Garbarino, Marco Lorenzi ... Daniel C Alexander
    Computational-driven, imaging-based topological profiles of neurodegeneration differ substantially in different neurodegenerative conditions, suggesting distinct modes of dependence of the pathological spread on the underlying connectivity.
    1. Neuroscience

    Speech and music recruit frequency-specific distributed and overlapping cortical networks

    Noémie te Rietmolen, Manuel R Mercier ... Daniele Schön
    The neural response to natural speech and music processing is mostly shared between the domains, with additional evidence for selectivity in distributed (i.e. not regional) and frequency-specific neural activity.
    1. Neuroscience

    The anterior paired lateral neuron normalizes odour-evoked activity in the Drosophila mushroom body calyx

    Luigi Prisco, Stephan Hubertus Deimel ... Gaia Tavosanis
    By participating in the microglomerular microcircuit in the Drosophila mushroom body calyx, the anterior paired lateral neuron normalizes odour-evoked representations at the calyx via inhibition proportional to the input strength and localized to the regions where those inputs are positioned.

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