1,708 results found
    1. Genetics and Genomics

    Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes

    Shuai Zhang, Ruixue Wang ... Lin Sun
    Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective

    Joseph Ackermann, Chiara Bernard ... Martine Ben Amar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Medicine

    Gamma Knife Stereotactic radiotherapy combined with tislelizumab as later-line therapy in pMMR/MSS/MSI-L metastatic colorectal cancer: A Phase II Trial Analysis

    Yiran Zhang, Hanyang Guan ... Jinghua Pan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles

    Xu Zheng, Shi Yu ... Guangxun Meng
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia

    Maria Ardaya, Marie-Catherine Tiveron ... Fabio Cavaliere
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Cell Biology

    Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction

    Jittoku Ihara, Yibin Huang ... Koichi Yamamoto
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Developmental Biology

    Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice

    Alexandra V Bruter, Ekaterina A Varlamova ... Victor V Tatarskiy
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Cell Biology
    2. Computational and Systems Biology

    Unbiased identification of cell identity in dense mixed neural cultures

    Sarah De Beuckeleer, Tim Van De Looverbosch ... Winnok H De Vos
    Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.
    1. Microbiology and Infectious Disease

    Secretory leukocyte protease inhibitor influences periarticular joint inflammation in B. burgdorferi-infected mice

    Qian Yu, Xiaotian Tang ... Erol Fikrig
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration

    Ana Patrícia Graça, Vadim Nikitushkin ... Gerald Lackner
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
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