The discovery of evolutionarily conserved macrophage subsets in zebrafish paves the way for a comprehensive study of macrophage behaviour and function.

Obesity leads to increased phosphatidylcholine turnover in adipose tissue macrophages that makes them susceptible to saturated fatty acid-induced inflammation.

The anti-tuberculosis drug bedaquiline reprograms human macrophages into potent bactericidal phagocytes, which are able to control bacterial infection.

Interleukin 4 signaling co-opts the Akt-mTORC1-Acly pathway to couple metabolic input to the control of energetically demanding processes during macrophage M2 activation.

A new type of skin perivascular macrophages with extramedullary origin, access to blood and exclusive anti-inflammatory reparative properties has been characterized.

Enriching the interactome with context-specific information from proteomics helps the identification of novel regulators of macrophage activation.

Detailed analysis of the sequence of monocyte differentiation into distinct gut tissue macrophages provides insights into monocyte biology and can serve as a platform for the design of cell therapies.

CCL5-dependent macrophage recruitment drives breast cancer recurrence through collagen deposition in residual tumors.

Type-I interferon enriched microenvironment generated by Mycobacterium tuberculosis induces the Siglec-1 receptor expression in human macrophages, including on tunneling nanotubes, and contributes to the exacerbation of cell-to-cell transfer of HIV-1.

A distinct resident macrophage subpopulation that localizes to the adipose stroma and fibrous capsule of the nulliparous mammary gland and to extracellular matrix-enriched stroma surrounding mammary tumors is identified.