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Tissue-level cell tracking and analysis of actomyosin and N-cadherin adhesion dynamics, coupled with disruption of the regulatory gene Shroom3, reveals region-specific cell behaviors along the anteroposterior axis during neural tube closure.

Electrical and biomechanical stimuli directly bias cortical signal transduction and cytoskeletal waves, and the direct bias induced by an electric field develops slowly compared to the rapid surface-receptor-mediated response to chemotactic gradients.

Pancreatic cancers can utilize hyaluronic acid, an abundant extracellular matrix component in the tumor microenvironment, to fuel cancer cell metabolism and growth.

Activation of Wnt/β-catenin signaling in endothelial progenitors derived from human pluripotent stem cells partially induces the specialized blood–brain barrier phenotype while the same treatment in matured endothelial cells is less efficacious.

Cationic cell-penetrating peptides (CPPs) enter cells through ~2 (–5)-nm-wide water pores induced by the strong negative plasma membrane potential that CPPs and the activity of potassium channels generate.

Hexosamine salvage through the enzyme N-acetylglucosamine kinase is stimulated in nutrient-limited conditions and supports pancreatic tumor growth.

Autoinhibition allows synaptic endocytic actin regulators to pre-deploy to synaptic membranes at high concentrations and constrains actin assembly to productive events.

Computer visualization techniques developed for video games can be repurposed to enable viewers to explore cells and their environment in three dimensions.

A high-throughput microscopy screen for drugs that modulate SARS-CoV-2 spike-mediated membrane fusion identifies an essential role for cholesterol in both virus entry and syncytia formation.