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    1. Neuroscience

    Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans

    Benjamin R Kop, Yazan Shamli Oghli ... Lennart Verhagen
    Realizing the clinical and neuroscientific potential of transcranial ultrasonic stimulation (TUS) requires careful control of the peripheral auditory confounds that underlie previously reported online motor inhibitory effects.
    1. Cell Biology

    Caveolae couple mechanical stress to integrin recycling and activation

    Fidel-Nicolás Lolo, Dácil María Pavón ... Miguel A del Pozo
    Caveolae regulate integrin mechanosensing by establishing a force threshold for activation and recycling.
    1. Biochemistry and Chemical Biology
    2. Epidemiology and Global Health

    Association of egg consumption, metabolic markers, and risk of cardiovascular diseases: A nested case-control study

    Lang Pan, Lu Chen ... Liming Li
    The associations of egg consumption with metabolic markers and of these markers with cardiovascular disease (CVD) risk showed opposite directions, which may partially explain the protective effect of moderate egg consumption on CVD in the Chinese population.
    1. Neuroscience

    Transcranial magnetic stimulation (TMS) inhibits cortical dendrites

    Sean C Murphy, Lucy M Palmer ... Matthew E Larkum
    Studying the activity of cortical neurons in rats reveals the subcellular effects of transcranial magnetic stimulation, which is used for the non-invasive treatment of a variety of brain disorders.
    1. Neuroscience

    Induced sensorimotor cortex plasticity remediates chronic treatment-resistant visual neglect

    Jacinta O'Shea, Patrice Revol ... Yves Rossetti
    Tonic disinhibition of left motor cortex during prism adaptation enhanced consolidation of sensorimotor and cognitive prism after effects, causing lasting clinical gains in three patient cases with chronic treatment-resistant visual neglect.
    1. Medicine

    Migraine monoclonal antibodies against CGRP change brain activity depending on ligand or receptor target – an fMRI study

    Hauke Basedau, Lisa-Marie Sturm ... Arne May
    Despite relative impermeability of the blood-brain barrier for calcitonin gene-related peptide antibodies used in migraine treatment, these antibodies induce certain and highly specific brain effects particularly in the hypothalamus which may be part of the mechanism of their efficacy.
    1. Neuroscience

    Causal manipulation of functional connectivity in a specific neural pathway during behaviour and at rest

    Vanessa M Johnen, Franz-Xaver Neubert ... Matthew F S Rushworth
    Functional connectivity in the human brain reflects changes in synaptic plasticity induced with repeated paired stimulation.
    1. Immunology and Inflammation

    Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells

    Herbert G Kasler, Intelly S Lee ... Eric Verdin
    The development of Natural Killer T Cells is controlled by Histone Deacetylase 7, a function that combined with its known role in thymic negative selection provides a potential mechanism explaining its association with tissue-specific autoimmunity in humans.
    1. Physics of Living Systems
    2. Cell Biology

    27 T ultra-high static magnetic field changes orientation and morphology of mitotic spindles in human cells

    Lei Zhang, Yubin Hou ... Xin Zhang
    An ultra-high static magnetic field changes mitotic spindle orientation in cells by exerting magnetic torques on both microtubules and chromosomes.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform

    Dirk H Siepe, Lukas T Henneberg ... K Christopher Garcia
    A proteo-genomic CRISPR activation screening workflow to accelerate the identification of novel interactions between the secreted and membrane proteome with the potential to define new biological processes and identify future therapeutic targets.