1,394 results found
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2

    Jiajie Diao, Jacqueline Burré ... Axel T Brunger
    Experiments on synthetic models of synaptic vesicles have shed new light on the role of the protein α-synuclein in the central nervous system.
    1. Neuroscience

    Decoding the neural mechanisms of human tool use

    Jason P Gallivan, D Adam McLean ... Jody C Culham
    Imaging experiments reveal that some brain regions do not distinguish between actions performed using tools and those performed using the hands, while others represent these two types of action separately.
    1. Chromosomes and Gene Expression

    The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability

    Lamia Wahba, Steven K Gore, Douglas Koshland
    When a protein involved in DNA repair malfunctions, it can anneal RNA molecules to DNA molecules, creating hybrids that increase the frequency of mutations in the DNA.
    1. Neuroscience

    Skill learning strengthens cortical representations of motor sequences

    Tobias Wiestler, Jörn Diedrichsen
    Detailed analysis of fMRI data shows that sequences of movements are associated with individual patterns of neural activity that become more distinct with training.
    1. Ecology
    2. Physics of Living Systems

    Spatial dilemmas of diffusible public goods

    Benjamin Allen, Jeff Gore, Martin A Nowak
    A simple model reveals the roles of colony geometry and diffusion rate in allowing microbes to cooperate by sharing public goods.
    1. Neuroscience

    Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons

    Zhong L Hua, Philip M Smallwood, Jeremy Nathans
    The signaling molecule Frizzled3 plays a part in the development of the nervous system by controlling the ability of motor neurons to form connections with distant target muscles.
    1. Neuroscience

    Interaction of plasticity and circuit organization during the acquisition of cerebellum-dependent motor learning

    Yan Yang, Stephen G Lisberger
    During learning, one climbing fiber input instructs plasticity that is expressed in the simple-spike responses of cerebellar Purkinje cells, and causes neural learning that may inhibit future climbing fiber instructions.
    1. Cell Biology
    2. Developmental Biology

    Coordinated genomic control of ciliogenesis and cell movement by RFX2

    Mei-I Chung, Taejoon Kwon ... John B Wallingford
    Systems-level analysis in vertebrate ciliated epithelial cells shows that the network of genes activated by the transcription factor Rfx2 controls the development, migration, insertion and function of these cells.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Single-molecule tracking of the transcription cycle by sub-second RNA detection

    Zhengjian Zhang, Andrey Revyakin ... Robert Tjian
    A new technique called fastFISH enables nearly real-time and stoichiometric detection of nascent RNA and the tracking of individual stages of transcription at the level of single-molecules.
    1. Neuroscience

    Fast transient networks in spontaneous human brain activity

    Adam P Baker, Matthew J Brookes ... Mark Woolrich
    Non-invasive MEG recordings reveal that patterns of spontaneous activity in the resting brain are shorter lived than previously thought.

Refine your results by:

Type
Research categories