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    1. Medicine
    2. Immunology and Inflammation

    A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies

    Thomas Balligand, Claire Carpenet ... Maarten Dewilde
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology

    The Molecular Logic of Gtr1/2 and Pib2 Dependent TORC1 Regulation in Budding Yeast

    Jacob H. Cecil, Cristina M. Padilla ... Andrew P. Capaldi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    The DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma

    Ariunaa Bayanjargal, Cenny Taslim ... Emily R Theisen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    Switching perspective: Comparing ground-level and bird’s-eye views for bees navigating clutter

    Annkathrin Sonntag, Odile Sauzet ... Olivier Bertrand
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Frontal beta-theta network during REM sleep

    Sujith Vijayan, Kyle Q Lepage ... Sydney S Cash
    Two regions of the frontal lobe – the anterior cingulate cortex and, unexpectedly, the dorsolateral prefrontal cortex – show coordinated rhythmic activity during REM sleep.
    1. Microbiology and Infectious Disease

    Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

    Elisa De Crignis, Tanvir Hossain ... Tokameh Mahmoudi
    Human liver organoids provide a patient-derived platform to interrogate host and viral mechanisms of HBV replication, perform anti-HBV and toxicity drug screens, and investigate the molecular determinants of related tumorigenesis.
    1. Evolutionary Biology

    Evidence for deliberate burial of the dead by Homo naledi

    Lee R Berger, Tebogo Makhubela ... John Hawks
    Not revised
    Reviewed Preprint v1
    • Landmark
    • Inadequate
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy

    Ricardo Guerrero-Ferreira, Nicholas MI Taylor ... Henning Stahlberg
    Two new polymorphic structures of recombinant human alpha-synuclein fibrils show striking differences to previous structures, while familial PD mutation sites remain crucial for protofilament interaction and fibril stability.
    1. Neuroscience

    Human cerebellum and ventral tegmental area interact during extinction of learned fear

    Enzo Nio, Patrick Pais Pereira ... Dagmar Timmann
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Evolutionary Biology

    Evolution and diversity of biomineralized columnar architecture in early Cambrian phosphatic-shelled brachiopods

    Zhiliang Zhang, Zhifei Zhang ... Guoxiang Li
    Columnar architectures, developed in early Cambrian phosphatic-shelled brachiopods, are highly biologically controlled and organic-matrix mediated, which sheds new light on the evolution and adaptation of biomineralization during the Cambrian explosion.
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